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Automated LNP Screening Across Liquid Handling Platforms

Formulate LNPs on your existing liquid handler with the LNP Screening Array.

Ready to start screening more LNP formulations?

Share your contact information and our team will reach out to discuss your liquid handler, screening goals, and next steps.

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Find your liquid handler

Run the LNP Screening Array with an automation protocol configured for your liquid handler, pipetting setup, and deck layout.

Using another liquid handler?

Check whether your platform can run the LNP Screening Array.

LNP performance across leading liquid handlers

Cross-platform characterization showed consistent particle size and PDI with the LNP Screening Array.

<60 nm
Z-average diameter

<0.15
PDI

<3%
Z-average %CV

Particle size and PDI for blank SM-102 LNPs across characterized liquid handlers.

Study conditions

Blank LNP characterization using an SM-102 lipid formulation.

Condition Setting
Lipid composition SM-102
Fluidic resistance ratio 3:1
Formulation volume 250 µL
Total flow rate 1.75 mL/min
DLS Malvern Zetasizer

Bring LNP formulation onto your liquid handler

The LNP Screening Array is a microfluidic consumable that formulates and collects LNPs directly on your liquid handler.

Platform-specific automation

Run a method configured for your liquid handler, pipetting setup, labware, and deck layout.

LNP Screening Array

Deliver lipid and aqueous inputs directly from pipette tips into eight independent microfluidic mixers.

Collected formulations

Recover each formulation separately for downstream processing and characterization.

Evaluate LNP screening on your liquid handler

Run the workflow in your lab with your own formulations and measure performance against your screening requirements.

Ready to start screening more LNP formulations?

Share your contact information and our team will reach out to discuss your liquid handler, screening goals, and next steps.

= required

FAQ

We run an evaluation in your lab using your liquid handler, formulations, and screening requirements. Our applications team configures the workflow, guides your team through the first formulations, and measures performance against success criteria established before the evaluation.

Learn more about evaluating the LNP Screening Array here.

Yes. Automation protocols are configured and tested for the liquid handler model and pipetting setup, including the associated labware and deck layout. A protocol developed for one model may require configuration and testing before use on another model from the same manufacturer.

Yes, additional liquid handlers can be assessed for compatibility.

We can review your platform for compatibility based on:

  • Instrument make and model
  • Pipetting configuration
  • Deck space
  • Formulation workflow

One LNP Screening Array supports up to eight independent formulations at 100–1,000 µL each. We confirm the working volume for your liquid handler during planning.

Yes. Your team supplies the lipids, cargo, solvent, buffers, and assay reagents, so you can evaluate the formulations relevant to your program.