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LNP Screening Array

Transform your liquid handler into an LNP screening platform.

Request Starter Array

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Parallel LNP Screening Array. A microplate-sized microfluidic device with four sets of flow-focusing mixers on the right and four sets of T-junction mixers on the left.

Automate your entire screening workflow.

Our LNP Screening Arrays run on the liquid handlers you already own.

Turn sample prep and formulation into a single, continuous workflow that keeps your entire discovery process on the deck.

No Expensive Instruments
No need to source, purchase, or install new equipment.

On-Deck Integration
Go from reagents-to-LNP without leaving the deck.

Formulate in Seconds
Create each new formulation in seconds to ramp throughput on demand.

Dedicated systems create bottlenecks.

Standalone instruments lock you into fixed geometries and isolate your workflow.

Bring screening onto your liquid handler to accelerate your formulation discovery.

Dedicated LNP systems LNP Screening Array
No $150K-$300K per instrument Yes No new equipment to purchase
No Incompatible with your liquid handler Yes Runs on the automation you already own
No Equipment bottlenecks slow development Yes Eliminate single points of failure
No Fixed geometries fail on complex formulations Yes Tune for target particle size and PDI
Parallel LNP Screening Array. A microplate-sized microfluidic device with four sets of flow-focusing mixers on the right and four sets of T-junction mixers on the left.

A scalable path from discovery to customization.

  1. Validate with the Starter Array.
    Use the multi-geometry Starter Array to identify the mixing approach and flow conditions that perform best for your formulation.
  2. Scale with the LNP Screening Array.
    Lock in your optimal geometry. Order LNP Screening Arrays configured with your target mixer to increase screening throughput.
  3. Go beyond basic mixing.
    Get expert design support to engineer your custom LNP Screening Array. We optimize for your automation constraints and targets for particle size, liquid volumes, and throughput.
  4. Receive custom arrays in one week.
    We use our Transition Molding technology to manufacture and ship your custom LNP Screening Arrays.

Unlock impossible formulations.

Standard mixers fail when you push boundaries.

Dedicated systems force you into a narrow operating window.

We build custom LNP Screening Arrays tuned to your exact constraints to screen the conditions standard instruments can’t handle.

Built for: Dedicated LNP Systems Custom LNP Screening Array
Your size targets No Yes
Your viscosities No Yes
Your flow rate ratios No Yes
Your volumes No Yes
Result: Fouling, clogging, and failure Optimized performance

Everything you need to start screening.

Starter Array

Designed to help you identify the optimal mixing geometry for your formulation in a single run.

Key Specifications:

  • Universal Compatibility - Works with any liquid handler, compatible with any tips.
  • Compare Geometries & Ratios - Evaluate multiple mixing techniques and flow conditions side-by-side to find the best fit for your application.

8x Staggered Herringbone Mixers

  • 4x Flow Focusing Mixers
  • 4x T-Junction Mixers
  • Flow Ratios: 1:1, 3:1, 5:1, 7:1

What's Included:

  • Starter Array
  • Automation Protocol Support
Top-down view of the Parallel LNP Screening Array. A microplate-sized microfluidic device with four sets of flow-focusing mixers on the right and four sets of T-junction mixers on the left.

Start screening LNPs on your liquid handler.

Transform your liquid handler into an LNP screening platform.

Start screening today on the automation you already own.

FAQ

Yes. Modern liquid handlers deliver <2% CV on dispense volumes. This precision is more than adequate for reproducible LNP synthesis. The physics of mixing remains the same whether you use the syringe pumps on a dedicated instrument or the automated channels on your liquid handler.

Yes. Unlike standard cartridges that clog or fail under high pressure, our custom LNP Screening Arrays are engineered specifically for your viscosity and flow rate constraints. This allows you to screen formulations that are impossible on off-the-shelf devices.

Supplement your dedicated system. Standalone instruments are excellent for scale-up but lock you into fixed mixer geometries and create scheduling queues. Use the LNP Screening Array to offload discovery to your liquid handler. This gives you access to custom mixing designs and distributes capacity without tying up your primary instrument.

No. We provide the specific automation parameters for your liquid handler. If you can run a standard sample prep protocol, you can run an LNP screen.

No. The LNP Screening Array is a consumable that runs on the automation you already own. There is no new instrument to buy, no service contract to sign, and no installation delay.